Table 2.

Versican mRNA Isoform Change in Cells on 400-nm Pitch Surfaces

Cells	V0	V1	V2	V3
HTM 631 No Dex	2.7*	2.1*	1.3*	1.3
HTM 631 Dex	1.2*	1.3	1.0	2.0*
HTM 682 No Dex	5.6*	3.0*	4.3*	4.0*
HTM 682 Dex	3.9*	1.8*	2.5*	1.3
HTM 701 No Dex	1.4*	1.4*	1.0	3.0*
HTM 701 Dex	0.6*	0.6*	1.5	1.0

Changes (n-fold) in the versican mRNA isoform levels (±SD) when HTM 631, 682, and 701 were grown on 400-nm pitch topography compared with planar surfaces for each condition. These comparisons were determined by dividing the change on the 400-nm pitch surface by the planar value. There were increases in the V0 and V1 isoforms with the control cells without dexamethasone (Dex), but values for the cells grown with 10⁻⁷ M dexamethasone were more variable.

^*Statistically significant difference between the 400-nm pitch surface and planar surface mRNA (Student’s t-test P < 0.05).