Figure 2.

Balb/c Rag-2^−/−Jak3^−/− mice support human hematopoietic stem cell engraftment more efficiently than C57/BL6 Rag-2^−/−Jak3^−/− mice. Cord blood-derived CD34⁺ cells (2 × 10⁵ cells/ mouse) were transplanted into irradiated newborn mice intrahepatically. Peripheral blood of CD34-transplanted recipients was obtained 12 weeks after transplantation, and human and murine chimerism was assessed by flow cytometry.