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. 2010 Oct 8;39(3):970–978. doi: 10.1093/nar/gkq886

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Deletion of EXO1 along with TDP1 results in an additive increase in additions. The accuracy of repair of plasmids of linearized DNA with 5′-extensions (HindIII, A and EcoRI, B) or 3′-extensions (PstI, C) was determined in exo1Δ tdp1Δ deleted strains. Results with wild-type and exo1Δ are the data presented in figure 2, and the data from the tdp1Δ deleted strain was published earlier (23). The overall level of inaccurate repair for exo1Δ tdp1Δ was compared with exo1Δ using Fisher’s exact test. For the HindIII digested DNA, P = 0.034; and for the EcoRI digested DNA, P = 0.008. The difference between any of the mutants with plasmid linearized with PstI was not significant.