Figure 7.

TPMPA augments excitatory currents in ON ganglion cells. A, Excitatory currents from an ON ganglion cell in control conditions and with TPMPA. B, Static nonlinearities from the same cell: TPMPA increased the slope of the linear portion, indicating an increase in gain. Inset, Scaling nonlinearities brings them into register, indicating no change in rectification. C, Most cells lie near the diagonal, indicating TPMPA caused no consistent change in rectification (5 ON β, 5 G2). D, TPMPA increased gain in most cells. E, Power spectra of excitatory currents: TPMPA increased power at all frequencies but increased power at low frequencies more, as shown by the normalized spectra in the inset. F, TPMPA reduced the middle frequency of the power spectrum for most cells.