Table 2.

Details of Previously Identified SNPs

Studies	Locus	Physical Location, Mb	Using SNP	SNP Type	Original SNP	Genes in Region	OHGS, OR (95% CI)
5	1p32	55.27	rs11206510	G	rs11206510	PCSK9	1.00 (0.91,1.10)*
2, 5	1p13	109.62	rs646776	I	rs646776	CELSR2/PSRC1/SORT1	1.18 (1.08,1.30)
5	1q41	220.87	rs17465637	G	rs17465637	MIA3	1.15 (1.06,1.25)
5	2q33	203.45	rs6725887	G	rs6725887	WDR12	1.28 (1.14,1.43)
7	3q22	139.60	rs9818870	G	rs9818870	MRAS	1.13 (1.02,1.25)
5	6p24	13.04	rs12526453	G	rs12526453	PHACTR1	1.11 (1.03,1.21)
8	6q26-27	160.88	CCTC haplo	H	rs3798220	SLC22A3/LPAL2/LPA	1.79 (1.38,2.31)
2-5	9p21	22.09	rs4977574	G	rs4977574	CDKN2A/CDKN2B	1.46 (1.35,1.57)
2, 5	10q11	44.10	rs1746049	G-T	rs1746048	CXCL12	1.17 (1.04,1.31)
6, 9	12q24	111.36	rs11066301	I	rs11066301	SH2B3/ATXN2/PTPN11	1.17 (1.08,1.26)
7	12q24	119.92	rs2259816	G	rs2259816	HNF1A/C12orf43	1.13 (1.04,1.22)
5	19p13	11.02	rs1122608	G	rs1122608	LDLR	1.20 (1.09,1.31)
5	21q22	34.52	rs9978407	G-T	rs9982601	SLC5A3/MRPS6/KCNE2	1.25 (1.12,1.40)

Original SNP refers to the SNP as identified through the relevant GWAS; using refers to the SNP being used in our analysis. SNP type refers to whether the SNP being used was the original genotype SNP (G), a tag SNP of the genotype SNP (G-T), an imputed SNP (I), or a haplotype (H). Odds ratios (ORs) and 95% confidence intervals (CIs) are given for the risk allele for a logistic regression model containing all 13 SNPs.

^*rs1120650 was removed after the model-fitting procedure.