TABLE 4.
Fine mapping of the 7p22 and 15q25 QTLs for log[HDL-C] after adjustment for age and gender
| Chromosome and Marker | Location | Map Position (cM) | Position (Mb) | Single-Point LOD | Multipoint LOD |
|---|---|---|---|---|---|
| Chr 7p | |||||
| D7S1532 | 7p22 | 3.13 | 2.4 | 0.19 | 1.04 |
| rs10499320 | 7p22 | 4.15 | 3.1 | 1.07 | 2.15 |
| D7S3056 | 7p22 | 7.0 | 4.5 | 1.60 | 3.09 |
| D7S3047 | 7p21 | 17.0 | 8.5 | 3.37 | 2.12 |
| Chr 15q | |||||
| D15S643 | 15q21 | 51.8 | 55.3 | 1.98 | 1.76 |
| D15S1507 | 15q22 | 59.8 | 60.9 | 2.54 | 2.73 |
| D15S983 | 15q23 | 66.9 | 66.4 | 0.79 | 1.30 |
| D15S818 | 15q24 | 71.8 | 70.7 | 2.35 | 2.75 |
| rs1491579 | 15q25 | 78.9 | 82.0 | 2.67 | 4.83 |
| rs11638634 | 15q25 | 82.8 | 85.7 | 2.80 | 5.47 |
| D15S655 | 15q25 | 82.8 | 85.8 | 4.48 | 5.63 |
| D15S652 | 15q26 | 89.8 | 88.7 | 3.42 | 5.51 |
Abbreviations: HDL-C, high density lipoprotein cholesterol; LOD, logarithm of odds; QTL, quantitative trait locus.