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Assessment of SNPs at chromosome 15q22-25 for association with HDL-C using a QTDT in GeneQuest
| Chromosome 15q22-25 | QTDT Analysis | ||
|---|---|---|---|
| SNP | Gene/Position | F | P |
| rs1800588 | LIPC/promoter | 5.05 | 0.0067 |
| rs690 | LIPC/exon 4 | 1.72 | 0.1791 |
| rs6083 | LIPC/exon 5 | 0.21 | 0.8128 |
| rs1491579 | SH3GL3/intron 4 | 1.56 | 0.2117 |
| rs11638634 | N/A | 0.58 | 0.5576 |
Abbreviations: HDL-C, high density lipoprotein cholesterol; QTDT, quantitative transmission disequilibrium test; SNP, single nucleotide polymorphisms.
