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. 2010 Jun;51(6):1513–1523. doi: 10.1194/jlr.M004812

Fig. 4.

Fig. 4.

Effect of miR-370 on the expression of miR-122 in HepG2 cells. A: Real-time PCR analysis of miR-122 following treatment of HepG2 cells with sense and antisense miR-370 or with miR-negative control. B: Real-time PCR analysis of SREBP-1c FAS, ACC1, and DGAT2 gene expression following treatment of HepG2 cells with miR-370 alone or combination of miR-370 and miR-122. Asterisks indicate statistically significant changes between miR control and miR-370–treated HepG2 cells (P < 0.001) and between miR-370/miR control and miR-370/as-miR-122–treated HepG2 cells (P < 0.001). ACC1, acyl-CoA carboxylase 1; dn-cJun, dominant negative cJun; Cpt1α, carnitine palmitoyl transferase 1α; DGAT2, diacylglycerol acyltransferase-2; miR, microRNA; SREBP-1c, sterol-regulatory element binding protein 1c.