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Effect of carvedilol on Fe2+/ascorbic acid induced protein carbonyl formation in brain cortex. Rat brain cortex homogenates (n=5–6 samples in each group) from 5–6 rats were used. The content of protein carbonyl groups was determined spectrophotometrically. The content of carbonyls in the presence of the pro-oxidative system without the drug tested was considered 100% (Ox+0). Effect of the drug tested on protein carbonyl content was monitored (Ox+1; Ox+3; Ox+10 µmol/l of carvedilol).
