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. Author manuscript; available in PMC: 2011 Feb 8.
Published in final edited form as: J Biol Chem. 2006 Jul 12;281(36):26665–26674. doi: 10.1074/jbc.M602174200

FIGURE 7. Fibrinogen is not essential for PAR-mediated platelet aggregation.

FIGURE 7

Washed platelets were supplemented with or without 100 μg/ml fibrinogen after pretreatment with or without 2-MeSAMP and BAPTA-AM (n = 3). A, fibrinogen had no apparent effect on platelet aggregation mediated by thrombin, PAR1-AP, or PAR4-AP. B, there was also no observed change in the level of aggregation either with or without supplemented fibrinogen. stim, stimulated.