Table 10.

Retrospective study results, significant improvement in patients (see Table 4) versus reported results in double-blind, placebo-controlled studies of patients taking atomoxetine

	Pilot study results	Atomoxetine studies
	AA with OCT assay interpretation	Study 129	Study 230	Study 331
n	85	618	36	84
% improved	77% (Table 4)	71%	54%	59%
% placebo improved	N/A	28%	40%	31%
% drug improvement over placebo	N/A	43%	14%	28%

Notes: The “% placebo improved” row represents percentage of subjects taking placebo who experienced significant remission of symptoms to the defined threshold of the study or greater. The bottom row is the advantage of the drug over placebo in the study cited.

Abbreviations: AA, amino acid; OCT, organic cation transporter.