Table 3. Description of three networks enriched for eQTL genes.
Associated terms | Gene Symbolsa |
Lipid Metabolism, Small Molecule Biochemistry, Post-Translational Modification | ACTN1, AKR7A2, CASP2, CASP4, CASP7, CCNE1, CTSD, CYP4F2, CYP4F3, DNAJA3, DUSP12, DYNLL2, DYNLT1, HNF4A, LSM3, MRPS14, PAWR, PNPO, PSMA1, RAP2C, RNF167, S100A1, SART3, SLC2A4, SOCS3, TIMM44, TXNDC12, UBE2M, ZFYVE20 |
Cell Cycle, Drug Metabolism, Lipid Metabolism | AIFM2, BYSL, CASP7, CBL, CCDC130, CCNE1, CEP70, COIL, ERH, FOLH1, GCSH, GPX8, GSTM1, GSTM4, GSTM5, IGSF21, LRBA, MAD1L1, MYO5B, MYO6, NID1, PINK1, PSME3, PTPRK, TGFB1, TP53, TSPYL2, ZBTB5, ZBTB16, ZNF24 |
DNA Replication, Recombination, and Repair, Cell Cycle, Cell Death | BCL2L12, CASP3, CASP7, CDK2, CENPC1, CKMT2, CTNNB1, CXCL12, DFFB, E2F4, EXOSC6, GAS2, HSH2D, KCNS3, LIMCH1, METAP1, MRPL14, MYC, OAS2, RFXANK, RNF17, SSX2IP, SUFU, WRN |
Gene symbols in bold denote genes with significant eQTL and overexpressed in animals carrying the Pietrain allele. Gene symbols that are underlined denote genes with significant eQTL and overexpressed in animals carrying the Duroc allele. Gene symbols in black denote genes in the network with no eQTL detected. Networks and associated terms were determined using the Igenuity Pathways Analysis software (Ingenuity Systems, Redwood City, CA, USA).