Fig. 1.
Effects of ovalbumin and D-4F on airway hyperresponsiveness to methacholine (MCh) challenge. Line graphs showing that OVA sensitization increases airway resistance to MCh challenge with respect to large airways RN, Newtonian resistance (A), tissue damping, G, (B), and tissue elastance, H, (C) and that 4F treatments reduce these measures to baseline. Line graphs for PBS-treated mice suggest that the PBS in which the D-4F was dissolved did not contribute to airway hyperresponsiveness. (N-PBS, Non-Sen PBS-treated, n = 11; N-D-4F, Non-Sen D-4F in PBS treated, n = 11; S-PBS, OVA-Sen PBS-treated, n = 10; S-D-4F, OVA-Sen D-4F-treated, n = 10).