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Summary of Overexpression Phenotypes in Zebrafish Embryos
| CE Defects | CE+ Eye Defects | Normal | p Value, Compared to prickle2 Wild-Type | |
|---|---|---|---|---|
| Uninjected (n = 58) | 0 | 0 | 100% | <0.01 |
| prickle2 wild-type (n = 139) | 79% | 34.5% | 20.1% | |
| prickle2Arg148His;Val153Ile (n = 205) | 88.3% | 28.3% | 11.7% | 0.045 |
|
prickle2Val605Phe (n = 148) |
66.2% | 34.5% | 33.8% | 0.012 |
