Table I.
Selected characteristics of gastric cancer cases and controls.
| Cases (n = 298), n (%) |
Controls (n = 417), n (%) |
p-Valuea | |
|---|---|---|---|
| Gender | |||
| Female | 100 (33.6) | 147 (35.3) | |
| Male | 198 (66.4) | 270 (64.7) | 0.64 |
| Age (years) | |||
| ≤59 | 92 (30.9) | 123 (29.5) | |
| 60–69 | 118 (39.6) | 164 (39.3) | |
| ≥70 | 88 (29.5) | 130 (31.2) | 0.88 |
| Education | |||
| Less than high school | 140 (47.0) | 158 (37.9) | |
| High school or technical training | 97 (32.6) | 124 (29.7) | |
| Some college/college graduate | 61 (20.4) | 135 (32.4) | 0.002 |
| Smoking statusb | |||
| Never | 85 (28.7) | 168 (40.3) | |
| Ex-smoker | 87 (29.4) | 133 (31.9) | |
| Current smoker | 124 (41.9) | 116 (27.8) | <0.001 |
| Alcohol usec | |||
| Non-drinker | 104 (35.8) | 138 (33.1) | |
| Former drinker | 97 (33.3) | 60 (14.4) | |
| Current drinker | 90 (30.9) | 219 (52.5) | <0.001 |
| Family history of cancerd | |||
| No family history | 175 (61.2) | 275 (67.1) | |
| Gastric cancer | 35 (12.2) | 18 (4.4) | |
| Other cancer | 76 (26.6) | 117 (28.5) | <0.001 |
| H. pylori infection statuse,f | |||
| Negative | 50 (16.8) | 61 (14.7) | |
| Positive | 248 (83.2) | 355 (85.3) | 0.44 |
| Lauren classificationg | |||
| Intestinal | 200 (70.9) | ||
| Diffuse | 50 (17.7) | ||
| Indeterminate | 32 (11.4) | ||
| Tumor localization | |||
| Cardia only | 34 (11.4) | ||
| Distal stomach | 218 (73.2) | ||
| Combined cardia/distal | 35 (11.7) | ||
| Unknown | 11 (3.7) | ||
| Stage of diseaseh | |||
| Localized | 59 (25.7) | ||
| Regional metastasis | 90 (39.1) | ||
| Displaced metastasis | 81 (35.2) | ||
| Tumor gradei | |||
| Well-differentiated | 15 (9.6) | ||
| Moderately differentiated | 78 (50.0) | ||
| Poorly differentiated | 63 (40.4) |
a
Based on χ2 test for categorical variables.
b
Data available for 296 cases.
c
Data available for 291 cases.
d
Data available for 286 cases and 410 controls.
e
Data available for 416 controls.
f
Negative = tested negative for both IgG antibodies to H. pylori and cagA; positive = tested positive for either IgG antibodies to H. pylori or cagA antibody, or both.
g
Data available for 282 cases.
h
Data available for 230 cases.
i
Data available for 156 cases.