Table II.

Odds ratios (ORs) and 95% confidence intervals (CIs) for gastric cancer risk by chemokine polymorphism, haplotypes, and frameshift deletion (CCR5).

	Cases	Controls	OR (95% CI)a	OR (95% CI)b
CCR2
rs1799864 G>A
GG	250	329	1.0 (ref)	1.0 (ref)
A carrier	46	88	0.8 (0.7–1.0)	0.8 (0.7–1.0)
CCR5
rs333 delta 32
++	225	331	1.0 (ref)	1.0 (ref)
+−	69	73	1.2 (1.0–1.4)	1.2 (1.0–1.4)
rs2734648 G>T
GG	133	192	1.0 (ref)	1.0 (ref)
T carrier	162	219	1.0 (0.9–1.2)	1.0 (0.9–1.2)
rs1799987 A>G
AA	93	142	1.0 (ref)	1.0 (ref)
G carrier	195	259	1.1 (0.9–1.3)	1.1 (0.9–1.3)
rs1800024 C>T
CC	241	326	1.0 (ref)	1.0 (ref)
T carrier	49	83	0.9 (0.7–1.1)	0.9 (0.7–1.1)
Haplotypesc
GAC	46.9%	49.5%	1.0 (ref)	1.0 (ref)
TGC	32.5%	31.2%	1.1 (0.9–1.4)	1.1 (0.8–1.4)
GGC	11.6%	8.9%	1.4 (1.0–2.0)	1.5 (1.0–2.2)
GAT	8.8%	10.3%	0.9 (0.6–1.3)	0.9 (0.6–1.3)
CX3CR1
rs3732379 G>A
GG	142	225	1.0 (ref)	1.0 (ref)
A carrier	153	188	1.1 (1.0–1.3)	1.1 (1.0–1.3)
rs3732378 C>T
CC	175	265	1.0 (ref)	1.0 (ref)
T carrier	117	144	1.1 (1.0–1.3)	1.1 (0.9–1.3)
Haplotypesd
GC	71.0%	72.9%	1.0 (ref)	1.0 (ref)
AT	21.1%	19.9%	1.1 (0.8–1.4)	1.1 (0.8–1.4)
AC	7.8%	7.2%	1.1 (0.7–1.7)	1.1 (0.7–1.6)
CXCL12
rs1801157 G>A
GG	193	258	1.0 (ref)	1.0 (ref)
A carrier	99	156	0.9 (0.8–1.1)	0.9 (0.8–1.1)

^aUnadjusted.

^bAdjusted for age, sex, smoking status, education.

^cHaplotypes with >1% frequency based on rs2724648, rs1799987, and rs1800024.

^dHaplotypes with >1% frequency based on rs3732379 and rs3732378.