Table III.
Chemokine polymorphism | No. of deaths | Person-years | Hazard ratio (95% CI)a | Hazard ratio (95% CI)b |
---|---|---|---|---|
CCR2 | ||||
rs1799864 G>A | ||||
GG | 219 | 9812.4 | 1.0 | 1.0 |
A carrier | 43 | 1287.6 | 1.4 (1.0–1.9) | 1.5 (1.1–2.1) |
CCR5 | ||||
rs333 delta 32 | ||||
++ | 195 | 8766.9 | 1.0 | 1.0 |
+− | 65 | 2244.6 | 1.2 (0.9–1.6) | 1.2 (0.9–1.6) |
rs2734648 G>T | ||||
GG | 126 | 3720.5 | 1.0 | 1.0 |
T carrier | 135 | 7378.6 | 0.7 (0.5–0.9) | 0.8 (0.6–1.0) |
rs1799987 A>G | ||||
AA | 87 | 2922.5 | 1.0 | 1.0 |
G carrier | 167 | 8103.8 | 0.8 (0.6–1.0) | 0.9 (0.7–1.2) |
rs1800024 C>T | ||||
CC | 210 | 9642.4 | 1.0 | 1.0 |
T carrier | 46 | 1374.5 | 1.4 (1.0–1.9) | 1.5 (1.1–2.1) |
CX3CR1 | ||||
rs3732379 G>A | ||||
GG | 125 | 5557.4 | 1.0 | 1.0 |
A carrier | 136 | 5539.2 | 1.1 (0.9–1.4) | 1.2 (0.9–1.5) |
rs3732378 C>T | ||||
CC | 157 | 6575.7 | 1.0 | 1.0 |
T carrier | 101 | 4503.8 | 1.0 (0.8–1.3) | 1.0 (0.8–1.3) |
CXCL12 | ||||
rs1801157 G>A | ||||
GG | 173 | 6791.9 | 1.0 | 1.0 |
A carrier | 85 | 4290.4 | 0.9 (0.7–1.1) | 1.0 (0.8–1.4) |
Unadjusted.
Adjusted for age, sex, smoking status, education, and stage of disease.