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. 2011 Jan 13;2011:235354. doi: 10.1155/2011/235354

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Copyright © 2011 Thomas G. Hampton et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(a) Gait signal of the left hindlimb of a TO-2 hamster superimposed over the gait signal of the left hindlimb of a F1B control hamster. Stride frequency was significantly higher and stride length significantly shorter in TO-2 dystrophic hamsters compared to F1B control hamsters. Propulsion duration (arrows) was significantly shorter in TO-2 hamsters compared to F1B control hamsters. This finding was consistent in hamsters studied at 1 month, 3 months, and 9 months of age. (b) The relative contributions of braking and propulsion to the stance duration of forelimbs and hindlimbs in 9-month-old F1B control hamsters and TO-2 delta-sarcoglycan-deficient hamsters walking at 16 cm/sec. The relative contributions of forelimb braking and propulsion to stance were significantly altered in TO-2 dystrophic hamsters (*P < .05, TO-2 versus F1B hamsters). Although propulsion duration was decreased in TO-2 hamsters, the contribution of propulsion to stance was not different.