Skip to main content
. Author manuscript; available in PMC: 2011 Feb 9.
Published in final edited form as: Biol Psychiatry. 2006 Mar 14;61(1):4–12. doi: 10.1016/j.biopsych.2006.01.006

Figure 4.

Figure 4

Effect of intraperitoneal (IP) injection of naltrexone (Ntx), at a dose ineffective per se (.25 mg/kg), on buprenorphine-induced increased ethanol intake (.03 mg/kg) in Marchigian Sardinian alcohol-preferring rats. Buprenorphine (Bup) was injected IP 5 min after Ntx administration, and ethanol was given to the animals 90 min after Bup. Alcohol consumption was monitored at 30, 60, 90, and 120 min. Values represent the mean (±SEM) of 10 subjects. Difference from control subjects: *p < .05. Veh, vehicle.