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. Author manuscript; available in PMC: 2011 Feb 9.
Published in final edited form as: Biol Psychiatry. 2006 Mar 14;61(1):4–12. doi: 10.1016/j.biopsych.2006.01.006

Table 2.

Locomotor Activity in Naïve Marchigian Sardinian Alcohol-Preferring Rats Treated With Buprenorphine, UFP-101, or Their Combination

Treatment Time Resting (min)
 Distance Traveled (cm)
Pretreatment Treatment Pretreatment Treatment
Veh + Veh 23.6 ± 1.4 23 ± 1.4 3717.6 ± 1232.5 3859.6 ± 972
UFP + Veh 22.9 ± 1.2 23.7 ± 1.3 3618.6 ± 615.5 3050.3 ± 715
Veh + Bup 23.6 ± 1 24.2 ± .7 3575 ± 709.1 2997.6 ± 393.2
UFP + Bup 24.6 ± 1.5 21.9 ± .2 3415 ± 1008.3 3961 ± 706.3

UFP-101 (20.0 μg/rat, intracerebroventricular was injected twice, 95 and 15 min before placing the animal into the open-field chambers. Buprenorphine (3.0 mg/kg, intraperitoneal) was given 90 min before placing the animal into the open-field chambers. Each value represents the mean (±SEM) of six subjects. Veh, vehicle; UFP, UFP-101; Bup, Buprenorphine.