Fig. 4.

Renal transplantation in a 13-year-old girl who had previously rejected two grafts. Subsequently she developed widely reactive T warm antibodies (to 99% of the population) making her a noncandidate for transplant. Eventually a kidney was obtained from a donor against whose lymphocytes the current recipient serum did not react, although stored serum still gave a positive crossmatch. The transplanted kidney survived the immediate immunologic insult and began to function within two weeks. She has had a good result.