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. 2010 Oct 21;1(10):e84. doi: 10.1038/cddis.2010.63

Figure 1.

Figure 1

Impact of the Hq mutation on acute cellular injury after IR. Representative microphotographs of the SVZ stained for AIF (a), active caspase-3 (b), TUNEL (c) or the oxidative stress marker 4HNE (d) in Wt and Hq mice in the contra- and ipsilateral hemisphere 6 h after IR. Bar=200 μm. Quantification of AIF- (e), active caspase-3- (f) TUNEL- (g) and 4HNE-positive (h) cells in the SVZ 6 h after IR is shown for Wt and Hq mice in the contra- and ipsilateral hemisphere. Data represent mean±S.E.M. *P<0.05, **P<0.01 and ***P<0.001, n=6 or 7 per group