Table 1.

Clusters showing significant fractional anisotropy (FA), mean diffusivity (MD), and axial diffusivity (AD) differences between males and females.

Anatomic Region	Cluster Size (Voxels)	MNI Coordinates*			Mean Value in Males	Mean Value in Females	Effect Size (Cohen’s d)†	Group Difference
		x	y	z
FA
Corticospinal tract L	503	19	18	46	0.58	0.62	1.43	F>M
Corticospinal tract R	249	−19	28	50	0.57	0.60	1.28	F>M
Superior corona radiata R	185	−26	18	34	0.47	0.49	0.91	F>M
MD
Inferior longitudinal fasciculus R	167	−42	34	−10	1.13	1.08	1.14	M>F
Forceps major L	167	15	91	9	1.14	1.09	1.38	M>F
AD
Corticospinal tract L	352	19	19	47	1.74	1.84	1.20	F>M
Corticospinal tract R	208	−20	29	50	1.70	1.79	1.26	F>M
Superior longitudinal fasciculus R	389	−43	7	30	1.60	1.52	1.67	M>F
Inferior longitudinal fasciculus R	358	−41	34	−9	1.91	1.82	1.45	M>F
Forceps minor R	186	−18	−33	16	1.91	1.83	1.01	M>F

^*Coordinates of the center of mass in clusters with significant gender differences

^†Effect size from the average t-value for each cluster

L=Left; R=Right; F=Female; M=Male