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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Hypertension. 2010 Nov 8;56(6):1069–1076. doi: 10.1161/HYPERTENSIONAHA.110.155721

Table 3.

rs13306560 and clinic BP in the GRAPHIC Study and validation cohorts

Study Informative
subjects
Minor (coded)
allele
clinic SBP clinic DBP
β (SE) P-value β (SE) P-value
GRAPHIC 2,020 * A −3.07 (1.06) 0.0039 −2.60 (0.68) 0.0001
CoLaus 5,356 * −1.20 (0.85) 0.1569 −1.16 (0.54) 0.0322
SCS 753 * −6.17 (3.01) 0.0407 −4.53 (1.74) 0.0094
Combined 8,129 * −2.12 (0.65) 0.0011 −1.87 (0.41) 5.4×10−6

CoLaus – Swiss population-based study; SCS – Silesian Cardiovascular Study; β - individual β-coefficient; SE – standard error; P – values were obtained from tests adjusted for age, age2, sex, antihypertensive treatment and familial correlations (where appropriate)

*

number of subjects with available genotype and phenotype information

rs13306560 was imputed in the CoLaus cohort (r2hat=0.88)

based on inverse variance-weighted fixed effects meta-analysis; P-values of heterogeneity test were 0.1512 and 0.0744 for SBP and DBP, respectively

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