Table 2.
Haematological parameters of alloxan-induced diabetic rats after four weeks of treatment with aqueous extract of Parquetina nigrescens and chlorpropamide. Values are expressed as mean ± SD.
| Group Haematological parameters |
Group A Control(5) |
Group B Extract alone (5) |
Group C Alloxan + Extract (5) |
Group D Alloxan alone (5) |
Group E Alloxan + chlorpropamide (5) |
| PCV % | 41.00 ± 6.04 | 41.80 ± 3.35 | 42.60 ± 2.51 | 28.8 ±10.08ab*c**e*** | 46.61 ± 2.88 |
| RBCx 106/µL) | 6.88 ± 1.31 | 6.72 ± 0.58 | 7.32 ± 0.56 | 5.05 ± 1.69ab*c** | 7.66 ± 0.21 |
| Hb g/dl | 13.00 ± 0.52 | 12.54 ± 0.95 | 12.60 ± 0.52 | 9.54 ± 3.37abc*e** | 13.86 ± 0.58 |
| MCV fl | 60.40 ± 4.34 | 62.40 ± 3.85 | 58.40 ± 2.97 | 57.00 ± 2.86 | 60.80 ± 2.68 |
| MCH pg | 20.00 ± 4.47 | 18.60 ± 1.14 | 17.20 ± 0.84 | 19.10 ± 1.46 | 18.00 ± 0.45 |
| MCHC g/dl | 32.60 ± 5.27 | 29.80 ± 1.48 | 29.60 ± 1.14 | 16.00 ± 0.25ace***b** | 30.00 ± 0.71 |
| Platelets × 103/µL) | 41.18 ± 0.35 | 43.20 ± 1.53 | 58.22 ± 3.77abd*** | 1.09 ± 0.25abc***e** | 64.78 ± 9.95abd** |
| WBC ×103/µL) | 8.22 ± 0.92bd*** | 5.48 ± 0.77 | 18.26 ± 10.6abde* | 5.76 ± 0.72 | 8.70 ± 2.80bd** |
Superscript alphabets are significantly different from their corresponding group. Asterisks indicate level of significance. * = P<0.05, ** = P<0.01, *** = P<0.001