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. Author manuscript; available in PMC: 2012 Mar 15.
Published in final edited form as: Neuroimage. 2010 Dec 23;55(2):622–628. doi: 10.1016/j.neuroimage.2010.12.048

Figure 4.

Figure 4

Quantitative analysis of the regional CBV change after cocaine injection. Peak amplitude and the time to peak of the gamma variate fit to the signal time course are shown for specific brain regions. The error bars indicate the standard error of the mean (N = 6 per group). In all ROIs there is a statistically significant difference (P < 0.01) between DAT KO and wildtype mice in at least one of the three fitting parameters (the shape factor α is not shown). The overall time course of the ΔCBV response is statistically different for KO and control mice in all ROIs except the thalamus. Typical ROI outlines are shown on two coronal brain slices: prefrontal, frontal and frontoparietal cortex (CTX), nucleus accumbens (ACB), caudate putamen (CP), amygdala (AMY), hippocampal formation (HPF), thalamic nuclei (TH), hypothalamus (HY), midbrain (MB), ventral tegmental area (VTA), substantia nigra (SN), pons (P), medulla (MY), cerebellum (CBX).