Fig. 7.

Comparative attenuation of OxLDL-induced secretion of cytokines by HDL and neo HDL. HDL and neo HDL attenuated OxLDL-induced IL-6 and TNF-α production in a dose-dependent manner (Supplemental Fig. 9). For the data shown here, OxLDL (100 μg/mL) was preincubated with 100 μg/mL of HDL or neo HDL for 1 h at 37 °C. Cells were then incubated with OxLDL, HDL, neo HDL, HDL + OxLDL and neo HDL + OxLDL for 16 h. IL-6 and TNF-α secretion were measured by ELISA. One-way ANOVA analysis with Tukey's post-test indicated the means were significant as indicated ***p < 0.001, **p < 0.01, *p < 0.05