Table 1.
Allelic frequencies
|
Genotypes
|
|||||
Subjects | Αα | -α3.7 | αα/αα | -α3.7/αα | -α3.7/-α3.7 | |
Euro-descendants | 0.98 | 0.02 | 192 (95.5)* | 9 (4.5) | 0 | |
African Brazilians | 0.88 | 0.12 | 147 (77.0) | 41 (21.5) | 3 (1.6) | |
p | < 0.001 | < 0.001 | < 0.001 | |||
Patients with microcytic anemia | 0.80 | 0.20 | 69 (68.3) | 23 (22.8) | 9 (8.9) | |
p§ | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.027 | |
p# | < 0.001 | < 0.001 | 0.01 | < 0.001 |
*Number of individuals and percentage (in parentheses). §,#compared with Euro-descendants and African Brazilians, respectively.