Table 2.
Factor |
|||||
---|---|---|---|---|---|
Lung Function | Ratio/BD response | Inflammatory/Atopy | Symptoms | Exacerbations | |
Pre-BD FEV1 | 0.979 | 0.161 | 0.024 | −0.044 | −0.056 |
Pre-BD FVC | 0.975 | −0.188 | 0.067 | −0.005 | −0.054 |
Pre-BD Peak Flow | 0.750 | 0.120 | 0.123 | −0.057 | −0.030 |
Pre-BD FEV1/FVC ratio | −0.085 | 0.942 | −0.133 | −0.106 | 0.012 |
FEV1 BD Responsiveness | −0.178 | −0.644 | 0.240 | 0.157 | 0.023 |
Serum IgE level (ng/ml)* | 0.100 | −0.078 | 0.692 | 0.049 | −0.037 |
No. of positive core skin tests | 0.132 | −0.017 | 0.583 | 0.109 | −0.002 |
Total Eosinophil Count (mm3)* | 0.007 | −0.122 | 0.520 | 0.003 | 0.027 |
FEV1 PC20 methacholine, mg/ml* | 0.109 | 0.292 | −0.428 | −0.193 | −0.066 |
Mean Symptom Score | 0.055 | −0.082 | 0.093 | 0.708 | 0.179 |
No. of days with albuterol puffs | −0.050 | −0.077 | 0.078 | 0.502 | 0.247 |
No. of episode-free days | 0.081 | 0.096 | −0.066 | −0.661 | 0.110 |
No. of doctor contacts | −0.014 | 0.013 | 0.020 | 0.085 | 0.571 |
No. of school absences | −0.037 | 0.021 | −0.072 | −0.025 | 0.541 |
No. of nights awakened | −0.034 | −0.067 | 0.095 | 0.218 | 0.359 |
No. of days with any prednisone use** | NA | NA | NA | NA | NA |
% Variance Explained† | 17.1% | 10.1% | 9.3% | 8.9% | 5.8% |
Data was logarithimically transformed for factor analysis
Participants were taken off of Prednisone during the 28 day screening period but could use it afterwards
Common variance explained by all 5 factors: 58.9%