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. 2010 Oct 20;588(Pt 24):5089–5104. doi: 10.1113/jphysiol.2010.198283

Table 1.

Passing–Bablok regression analysis comparing ‘traditional’ and ‘one-sample’ approaches to measure red blood cell glutathione FSR

Regression analysis 1
Variable X Variable Y
Absolute glutathione FSR values (traditional equation) Absolute glutathione FSR values (one-sample equation)
Value 95%c.i.
Intercept A −0.02 from −11.32 to 7.01
Slope B 0.86 from 0.68 to 1.04
Cusum test for linearity No significant deviation from linearity (P > 0.05)
Regression analysis 2
Variable X Variable Y
Glutathione FSR changes (traditional equation) Glutathione FSR changes (One-sample equation)
Value 95%c.i.
Intercept A 0.95 from −9.10 to 1.47
Slope B 0.91 from 0.75 to 1.20
Cusum test for linearity No significant deviation from linearity (P > 0.05)

Table shows results of two separate regression line analyses performed by the Passing–Bablok method (see Fig. 5). Regression analysis 1 was performed to compare absolute glutathione fractional synthesis rate (FSR) values measured by ‘traditional’ approach (X variable) with the same values measured by the ‘one-sample’ (Y variable) approach. Regression analysis 2 was performed to compare changes from baseline to day 7 and to day 33 of glutathione FSR measured by the traditional equation (Variable X), with the same values measured by one-sample equation (Variable Y). Both analyses show inclusion in the relative confidence interval (95%c.i.) of each Intercept A and Slope B value characterizing obtained regression lines. Additionally, in both analyses linear distribution was confirmed by an appropriate test.