Table 1.
Abnormal head shape of Mgrn1 null mutant mice.
| Measurement (SD)1 |
|||
|---|---|---|---|
| Skull element2 | Mgrn1md-nc/+ | Mgrn1md-nc/md-nc | % difference3 |
| Length: snout-frontal | 14.16 (0.48) | 13.59 (0.52) | −4.0 (p<0.0001) |
| n=21 | n=37 | ||
| Length: snout-parietal | 17.86 (0.29) | 17.08 (0.67) | −4.4 (p<0.0001) |
| n=20 | n=34 | ||
| Width of frontal | 5.98 (0.63) | 6.67 (0.28) | 11.5 (p<0.0001) |
| n=26 | n=42 | ||
| Width of parietal | 9.77 (0.13) | 9.14 (0.22) | −6.4 (p<0.0001) |
| n=17 | n=34 | ||
| Height of vault | 6.88 (0.14) | 7.63 (0.18) | 10.9 (p<0.0001) |
| n=20 | n=34 | ||
1
In millimeters, measured with digital calipers; SD: standard deviation.
Sample sizes (n) are variable as some skull structures were damaged during preparation/handing and could not be measured.
2
Elements measured as indicated in Figure 3c,f.
3
Mgrn1 null mutants smaller than wild-type when value is negative, larger when value is positive.