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. 2011 Feb 9;6(2):e16295. doi: 10.1371/journal.pone.0016295

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Lundgren et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The stem cells, indicated by arrows, are slender cells located between the Paneth cells (PC) at the very base of the crypts [17], [26]. The left part of the figure indicates that the muscarinic receptor M3 is located to the plasma membrane of the presumed intestinal stem cells. The tissue section in the right panel was only exposed to the secondary antibody. Mayer's haematoxylin. CL = crypt lumen.