Table 2.
Hits organized by genes in the K/P JAK/STAT screen.
| Gene | Number of dsRNAs | Number of scoring dsRNAs | Number of non-scoring dsRNAs | Category | Expressed in S2R+ Cells |
|---|---|---|---|---|---|
| Abl | 4 | 4 | 0 | 1 | Yes |
| CycA | 3 | 3 | 0 | 1 | Yes |
| dome | 3 | 3 | 0 | 1 | Yes |
| hop | 3 | 3 | 0 | 1 | Yes |
| mts | 2 | 2 | 0 | 1 | Yes |
| CycE | 3 | 2 | 1 | 2 | Yes |
| Pp4-19C | 4 | 2 | 2 | 2 | Yes |
| CG17090 | 3 | 2 | 1 | 2 | Yes |
| puc | 3 | 2 | 1 | 2 | Yes |
| CG34318 | CG8179 | 4 | 1 | 3 | 3 | No |
| CanA1 | 3 | 1 | 2 | 3 | No |
| CG4839 | 3 | 1 | 2 | 3 | No |
| CG7597 | 3 | 1 | 2 | 3 | Yes |
| CG9389 | 3 | 1 | 2 | 3 | No |
| mtm | 3 | 1 | 2 | 3 | Yes |
| Pi3K21B | 3 | 1 | 2 | 3 | Yes |
| smi35A | 3 | 1 | 2 | 3 | Yes |
| Src42A | 3 | 1 | 2 | 3 | Yes |
| CG8509 | 2 | 1 | 1 | 3 | No |
| gskt | 2 | 1 | 1 | 3 | No |
| htl | 2 | 1 | 1 | 3 | No |
| Myt1 | 2 | 1 | 1 | 3 | Yes |
| Pp1-Y2 | 2 | 1 | 1 | 3 | No |
| S6k | 2 | 1 | 1 | 3 | Yes |
Genes were included on this list if at least one dsRNA yielded a Z-score of +/- 2 or better across both replicates. The number of dsRNAs in the K/P set is indicated as well as the number of those dsRNAs that were scored in the screen with a Z-score with an absolute value of 1.5 or better. Genes were binned into 3 categories: Category 1 contains genes where 4 out of 4 or 3 out of 3 or 2 out of 2 dsRNAs scored. Category 2 contains genes where 2 out of 3 or 2 out of 4 or 3 out of 4 dsRNAs scored. Category 3 contains genes where only 1 dsRNA scored. A gene was defined to be expressed in S2R+ if the FPKM value was greater than 1.