Table 4.
Effect of supplementation of a hydrogenated trans fat and a corn-oil based low trans structured fat on plasma, hepatic and fecal lipid levels in apo E-/- mice.
| CS | LC | |
|---|---|---|
| Plasma lipids | ||
| Free fatty acid (mmol/L) | 1.14 ± 0.03 | 1.11 ± 0.04 |
| Triglyceride (mmol/L) | 1.46 ± 0.09 | 2.09 ± 0.08*** |
| Total-C (mmol/L) | 16.45 ± 0.81 | 18.75 ± 0.37* |
| HDL-C (mmol/L) | 0.11 ± 0.02 | 0.81 ± 0.06*** |
| HDL-C/Total-C (%) | 0.60 ± 0.06 | 4.06 ± 0.39*** |
| Atherogenic indexa | 174.95 ± 18.05 | 23.39 ± 1.99*** |
| Apo A-I (mg/dL) | 4.46 ± 0.57 | 7.47 ± 0.25*** |
| Apo B (mg/dL) | 21.00 ±0.54 | 17.19 ± 0.60*** |
| Hepatic lipids | ||
| Cholesterol (mmol/g liver) | 7.88 ± 0.03 | 5.83 ± 0.19*** |
| Triglyceride (mmol/g liver) | 7.21 ± 0.34 | 5.27 ± 0.18** |
| Fecal lipids | ||
| Cholesterol (μmol/g) | 4.60 ± 0.28 | 6.44 ± 0.37** |
| Triglyceride (μmol/g) | 2.22 ± 0.54 | 4.44 ± 0.85* |
Data are mean ± S.E. (n = 10). Values are significantly different from the CS group according to Student's t test: *P < .05, **P < .01, ***P < .001. C:cholesterol.
a Atherogenic index: (Total-C-HDL-C)/HDL-C
CS, commercial shortening; LC, low trans structured fat from corn oil