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. 2011 Feb 9;6(2):e16732. doi: 10.1371/journal.pone.0016732

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MacIntyre et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Samples of CMp11 were collected at 24 h intervals for 3 days. Following each collection, culture media was replaced with fresh TeSR-1 media (A) PCA analysis revealed a clear time related differences in the metabolic component of CMp11. (B) Analysis of corresponding loadings plots showed decreased formation of lactate and pyruvate, decreased utilisation of glucose, and increased concentrations of acetate and EtOH were characteristic of samples collected after 72 h.