Table 2. Genome-wide linkage results for VEGF serum levels in the three populations and combined sample.

Sample	Chromosome	Marker	Location (cM)	Mean LOD score (min - max)*	q-value
Campora	2p16.3	D2S2156	78.42	1.98 (0.70–2.64)	0.016
	6p21.1	D6S459	72.6	7.52 (3.78–10.19)	2.10E-13
	20q13.13	D20S178	75.47	1.94 (0.86–3.47)	0.022
Gioi	6p21.1	D6S459	72.6	5.31 (1.40–7.85)	3.92E-04
Cardile	6p21.1	D6S282	68.36	6.56 (3.22–9.10)	7.01E-05
Combined sample	3p26.3	D3S4559	1.08	2.68 (0.83–4.04)	0.012
	6p21.1	D6S459	72.6	13.94 (9.15–18.99)	7.27E-22

For each sample the mean LOD scores over all sub-pedigree sets and the corresponding q-value are reported.

*value of the maximum and minimum LOD scores observed over all sub-pedigree sets.