Table 4. Association results between the SNPs in the VEGF gene and the protein levels in the detection samples.

SNP	Campora (N = 42)			Gioi (N = 49)			Cardile (N = 45)
	MAF	Effect (CI 95%)	p-value	MAF	Effect (CI 95%)	p-value	MAF	Effect (CI 95%)	p-value
rs699947 *	0.41	−0.19 (−0.71; 0.34)	0.486	0.43	−0.22 (−0.66; 0.23)	0.339	0.44	−0.01(−0.45; 0.43)	0.961
rs833061 *	0.42	−0.18 (−0.56; 0.20)	0.353	0.50	0.26 (−0.22; 0.74)	0.287	0.50	−0.10 (−0.62; 0.43)	0.715
rs1570360 *	G = 0.46	0.17 (−0.18; 0.53)	0.331	A = 0.39	0.46 (0.01; 0.92)	0.043	A = 0.32	−0.12 (−0.73; 0.48)	0.696
rs2010963 *	0.43	−0.06 (−0.55; 0.43)	0.799	0.35	0.04 (−0.39; 0.48)	0.840	0.40	−0.43 (−0.90; 0.04)	0.070
rs25648 *	0.08	1.34 (0.49; 2.20)	2.11E-03	0.08	0.64 (−0.04; 1.33)	0.066	0.20	−0.05 (−0.62; 0.52)	0.862
rs2146323	0.33	−0.16 (−0.70; 0.38)	0.555	0.19	−0.83 (−1.35; −0.32)	1.55E-03	0.28	−0.34 (−0.94; 0.27)	0.275
rs3025020	0.46	0.95 (0.53; 1.37)	1.01E-05	0.26	0.21 (−0.30; 0.72)	0.414	0.22	0.47 (−0.08; 1.01)	0.093
rs3025039	0.14	−1.22 (−1.93; −0.51)	7.45E-04	0.12	0.25 (−0.35; 0.85)	0.418	0.18	−0.04 (−0.68; 0.61)	0.906
rs41282644	0.00	---	---	0.07	0.31 (−0.52; 1.13)	0.463	0.10	1.27 (0.51; 2.03)	1.03E-03

The SNPs significantly associated in the detection sample of each population are reported. The results for the SNP (*) repeatedly associated with VEGF levels and/or related diseases in the literature are also presented.

p-value threshold corrected for multiple testing = 0.003.