Table 2.
Frequencies of the platelet receptor GPIIIa PlA1/A2 and FcγRIIa H131R polymorphisms in 40 patients with infective endocarditis compared to 160 healthy volunteers.
| Platelet receptor genotype | Infective endocarditis patients, n = 40 (%) | Healthy volunteers, n = 160 (%) | P valuea | Healthy volunteers n = 88b | Healthy volunteers n = 31c |
|---|---|---|---|---|---|
| GPIIIa PlA1/A2 | |||||
| PlA1/A1 | 29 (72%) | 126 (78%) | 0.675 | 58 | 17 |
| PlA1/A2 | 10 (25%) | 30 (19%) | 26 | 10 | |
| PlA2/A2 | 1 (3%) | 4 (3%) | 4 | 4 | |
| FcγRIIa H131R | |||||
| H/H | 11 (28%) | 39 (24%) | 0.774 | 23 | 7 |
| H/R | 19 (47%) | 72 (45%) | 40 | 16 | |
| R/R | 10 (25%) | 49 (31%) | 25 | 8 | |
a
The P value was determined using the chi-squared test.
b
Platelet receptor genotype for healthy volunteers selected for platelet aggregation studies using PRP.
c
Platelet receptor genotype for healthy volunteers selected for flow cytometric studies and platelet aggregation studies using washed platelets.