Figure 4.

Sensitivity analysis of isolated changes of ventricular parameters on P _sys, P _dia and P _mean (upper panels), and to K _sys = P _sys/P _mean and K _dia = P _dia/P _mean (lower panels). Results are shown for varying heart rate (HR), end-systolic and end-diastolic ventricular elastance (E _es and E _ed), intercept volume (V ₀), time to reach end-systole (t _es) and venous filling pressure (P _v). For all simulations model parameters from group 1 in table 1 were used. Systole is indicated by thick lines, diastole by thin lines, and mean pressure by dashed lines