Table II.
Demographic and clinical characteristics at enrollment and length of follow-up of subjects included in the six longitudinal spirometric patterns. Total N is 1368, unless otherwise specified.
| Longitudinal Spirometric Patterns |
|||||||
|---|---|---|---|---|---|---|---|
| Consistent Normal (N = 913) | Recurrent Restrictive (N = 69) | Inconsistent Restrictive (N = 62) | Recurrent Obstructive (N = 155) | Inconsistent Obstructive (N = 54) | Mixed Restr/Obstr (N = 115) | P * | |
| Age in years: mean ± SD | 44 ± 17 | 62 ± 15 | 55 ± 17 | 60 ± 13 | 55 ± 17 | 64 ± 11 | N/A |
| Sex: % female | 59.1 | 76.8 | 69.4 | 38.7 | 59.3 | 67.0 | <0.001 |
| Obesity (n = 1325): % with BMI ≥ 30 Kg/m2 | 6.3 | 15.4 | 16.7 | 3.3 | 9.6 | 12.5 | 0.006 |
| Ever smoking (n = 1367): % with ≥ 1 pack-year | 48.4 | 37.7 | 50.0 | 82.6 | 73.6 | 58.3 | <0.001 |
| Physician confirmed asthma (n = 1366): positive % | 6.4 | 10.3 | 4.8 | 33.5 | 13.0 | 21.7 | <0.001 |
| Eosinophilia (n = 1035): positive % | 7.1 | 6.3 | 10.9 | 14.0 | 14.0 | 13.8 | 0.05 |
| Total serum IgE in IU/ml (n = 1221): geometric mean | 25.2 | 19.3 | 29.1 | 52.2 | 25.7 | 23.3 | <0.001 |
| Total follow-up in years: mean ± SD | 12 ± 7 | 7 ± 7 | 10 ± 7 | 9 ± 7 | 10 ± 7 | 11 ± 7 | <0.001 |
*
P value for the comparison across the six groups after adjustment for age.
No statistical pair comparisons were completed because of the number of groups.