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. Author manuscript; available in PMC: 2011 Feb 10.
Published in final edited form as: Neuromolecular Med. 2010 Mar;12(1):27–43. doi: 10.1007/s12017-009-8109-7

Fig. 5.

Fig. 5

Surface map indicating the overlap between regions of highest PiB-PET retention and aberrant default network fMRI activity in 35 non-demented older individuals. The panel on right demonstrates similar pattern of aberrant default network activity during memory encoding in patients with Alzheimer’s disease (Panel A) and in non-demented older individuals with high amyloid burden (PiB+ in Panel B) (Sperling et al. 2009)