Table 4.
Univariate logistic regression analysis of the variables associated with xanthelasma.
| Variables | Category | p-value | Odds ratio | 95% confidence interval |
| Age (years) | Continuous | 0.225 | 1.01 | 0.99-1.04 |
| Gender | Male | 0.883 | 1.04 | 0.59-1.86 |
| APOEHhaI | APOE*2 allele | 0.255 | 1.91 | 0.63-5.79 |
| APOE*3 allele | 0.129 | 7.86 | 0.43-142.55 | |
| APOE*4 allele | 0.363 | 0.67 | 0.28-1.59 | |
| APOBXbaI | X+ allele | 0.917 | 1.03 | 0.57-1.88 |
| X- allele | 0.845 | 1.09 | 0.46-2.60 | |
| APOBIns/Del | I allele | 0.694 | 1.18 | 0.52-2.70 |
| D allele | 0.272 | 0.72 | 0.40-1.30 | |
| LDLRAvaII | A+ allele | 0.302 | 0.65 | 0.29-1.47 |
| A- allele | 0.078 | 3.44 | 0.87-13.56 | |
| LDLRHincII | H+ allele | 0.429 | 1.46 | 0.57-3.70 |
| H- allele | 0.219 | 0.69 | 0.38-1.25 | |
| Total cholesterol (mg/dL) | Continuous | 0.560 | 0.99 | 0.99-1.01 |
| LDL-c (mg/dL) | Continuous | 0.991 | 1.00 | 0.99-1.01 |
| HDL-c (mg/dL) | Continuous | 0.655 | 1.01 | 0.97-1.04 |
| VLDL-c (mg/dL) | Continuous | 0.014# | 0.95 | 0.91-0.99 |
| Triglycerides (mg/dL) | Continuous | 0.014# | 0.99 | 0.98-0.99 |
| TC/HDL-c | Continuous | 0.426 | 0.91 | 0.72-1.15 |
| LDL-c/HDL-c | Continuous | 0.691 | 0.95 | 0.73-1.24 |
| TG/HDL-c | Continuous | 0.049 | 0.77 | 0.59-0.99 |
+/- = presence/absence of a restriction site. Ins/Del, insertion/deletion. HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; VLDL-c, very low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglycerides. #Statistically significant difference considering variable associated to xanthelasma.