Table 1.
Clinical information and agreement between invasive language mapping and fMRI results of brain tumor patients
| No. | Gender/ age |
EHI | Diagnosis | Tumor location/ size (cm3) |
Language | Impression of language from intra-operative language mapping and clinical findings |
Clinical findings more consistent with |
||
|---|---|---|---|---|---|---|---|---|---|
| Pre-op | Post-op | BL | ER | ||||||
| 1▴ | M/43 | 65 | Ganglioglioma WHO grade I–II | Left temporal/2.91 | Normal | Normal | Left hemisphere dominance for language | √ | √ |
| 2* | F/55 | 100 | Metastatic adenocarcinoma | Left temporal/7.58 | Normal | Normal | Left hemisphere involvement of language | √ | |
| 3* | F/30 | 100 | Glioblastoma WHO grade IV | Left temporal/38.42 | Speech difficulty | Better | Tumor surrounding areas involvement of language | √ | |
| 4 | M/43 | −100 | Glioblastoma WHO grade IV | Right temporal/40.83 | Normal | Normal | No language areas in the region of lesion | √ | |
| 5* | M/50 | 100 | Anaplastic oligoastrocytoma WHO grade III | Left temporal/7.27 | Occasional word-finding difficulty | Occasional word-finding difficulty → normal | Language areas were in the left hemisphere, and posterior to lesion | √ | |
| 6* | F/66 | 100 | Metastatic adenocarcinoma | Left parietal/1.67 left temporal/0.20 | Normal | Normal | No critical language areas immediately adjacent to lesion | √ | √ |
| 7 | M/35 | 100 | Oligoastrocytoma WHO grade II | Left frontal/19.62 | Normal | Normal | N/A | N/A | N/A |
| 8* | F/57 | 100 | Glioblastoma WHO grade IV | Left temporal/8.59 | Speech difficulty | N/A | No critical language areas in the region of lesion | √ | √ |
EHI: Edinburgh Handiness Inventory; positive EHI indicates right-handedness, negative EHI indicates left-handedness. BL: blocked design; ER: rapid event-related design.
Patient #1 had Wada test, which indicated left lateralization for language function.
Patients #2, #3, #5, #6, and #8 had intra-operative ECS testing.