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. Author manuscript; available in PMC: 2011 Feb 10.
Published in final edited form as: Neuroimage. 2008 Dec 6;47(Suppl 2):T107–T115. doi: 10.1016/j.neuroimage.2008.11.020

Table 1.

Clinical information and agreement between invasive language mapping and fMRI results of brain tumor patients

No. Gender/
age
EHI Diagnosis Tumor location/
size (cm3)
Language Impression of language from
intra-operative language
mapping and clinical findings
Clinical findings
more consistent
with


Pre-op Post-op BL ER
1 M/43 65 Ganglioglioma WHO grade I–II Left temporal/2.91 Normal Normal Left hemisphere dominance for language
2* F/55 100 Metastatic adenocarcinoma Left temporal/7.58 Normal Normal Left hemisphere involvement of language
3* F/30 100 Glioblastoma WHO grade IV Left temporal/38.42 Speech difficulty Better Tumor surrounding areas involvement of language
4 M/43 −100 Glioblastoma WHO grade IV Right temporal/40.83 Normal Normal No language areas in the region of lesion
5* M/50 100 Anaplastic oligoastrocytoma WHO grade III Left temporal/7.27 Occasional word-finding difficulty Occasional word-finding difficulty → normal Language areas were in the left hemisphere, and posterior to lesion
6* F/66 100 Metastatic adenocarcinoma Left parietal/1.67 left temporal/0.20 Normal Normal No critical language areas immediately adjacent to lesion
7 M/35 100 Oligoastrocytoma WHO grade II Left frontal/19.62 Normal Normal N/A N/A N/A
8* F/57 100 Glioblastoma WHO grade IV Left temporal/8.59 Speech difficulty N/A No critical language areas in the region of lesion

EHI: Edinburgh Handiness Inventory; positive EHI indicates right-handedness, negative EHI indicates left-handedness. BL: blocked design; ER: rapid event-related design.

Patient #1 had Wada test, which indicated left lateralization for language function.

*

Patients #2, #3, #5, #6, and #8 had intra-operative ECS testing.