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. Author manuscript; available in PMC: 2011 Feb 10.
Published in final edited form as: Circ Res. 2010 Dec 9;108(2):210–218. doi: 10.1161/CIRCRESAHA.110.231258

Figure 3. QCR in electrically paced cardiomyocytes.

Figure 3

A, Simultaneous measurement of diastolic QCR (rhod-2) (top) and QCD (fluo-5N) (middle) events in a paced (0.5 Hz) cardiomyocyte. Ticks to the left of the bottom image mark locations of the Z-disks. Traces on the bottom show time courses of 2 QCR-QCD events identified during diastole along with the transient. The traces of the QCR-QCD events have been enlarged in the inserts. B, Frequency of sparks and QCR events (* P<0.05). C, Averaged spark and QCR signal mass (* P<0.05). D, Summed Ca2+ leak of sparks or QCR events.