TABLE 1.
Cohort Characteristics by Coronary Calcium Status
| Characteristic | CAC > 0 (n = 423) | CAC = 0 (n = 495) | P-value* |
|---|---|---|---|
| Age at screening† (years) | 55.6 (2.7) | 54.8 (2.9) | <0.01 |
| Age at menopause† (years) | 43.4 (7.7) | 43.8 (7.2) | 0.30 |
| Body Mass Index (kg/m2) | 31.6 (6.2) | 29.8 (6.1) | <0.01 |
| Waist circumference† (cm) | 95.1 (13.7) | 88.7 (14.2) | <0.01 |
| Hip circumference† (cm) | 113.3 (13.0) | 110.4 (13.1) | <0.01 |
| Pack years of smoking† | 13.6 (19.5) | 7.5 (14.7) | <0.01 |
| Hypertension‡ | 44.4 | 30.5 | <0.01 |
| Dyslipidemia‡ | 14.2 | 6.7 | <0.01 |
| Diabetes‡ | 6.9 | 3.0 | 0.01 |
| Family history of CHD‡ | 48.7 | 46.0 | 0.52 |
| Physical Activity† (MET-hours/week) | 8.9 (12.2) | 11.0 (13.8) | 0.04 |
| History of any VMS† | 51.5 | 56.7 | 0.24 |
| VMS severity at baseline | 0.75 | ||
| - None | 41.4 | 39.2 | |
| - Mild | 33.6 | 36.1 | |
| - Moderate/Severe | 25.0 | 24.7 | |
| Duration of VMS‡ | 0.87 | ||
| - < 5 years | 18.2 | 22.7 | |
| - 5 to <10 years | 25.5 | 25.9 | |
| - 10 to < 15 years | 20.8 | 21.1 | |
| - ≥ 15 years | 35.5 | 30.3 | |
| HRT use status‡ | 1.00 | ||
| - Never used | 45.4 | 47.3 | |
| - Past user | 32.6 | 30.5 | |
| - Current user | 22.0 | 22.2 | |
| Bilateral oophorectomy‡ | 39.8 | 37.2 | 0.72 |
*
Adjusted for age;
†
Mean (SD),
‡
Percent (Frequency)