TABLE 2.
Distribution of Study Variables by the Presence/Absence of Vasomotor Symptoms
| Continuous Variables | VMS (Yes) | VMS (No) | p-value* |
|---|---|---|---|
| Mean (SD) | Mean (SD) | ||
| Age at screening (years) | 55.1 (2.9) | 55.3 (2.8) | 0.35 |
| Body-mass index (kg/m2) | 30.4 (6.1) | 31.4 (6.6) | 0.04 |
| Waist circumference (cm) | 91.1 (14.1) | 93.3 (14.9) | 0.05 |
| Hip circumference (cm) | 111.3 (13.2) | 112.8 (12.9) | 0.15 |
| Systolic BP (mm Hg) | 124.8 (15.5) | 123.4 (16.6) | 0.21 |
| Diastolic BP (mm Hg) | 77.7(8.7) | 77.1 (9.6) | 0.35 |
| Pack years of smoking | 10.6 (17.8) | 9.7 (16.1) | 0.5 |
| Total energy expenditure/wk (MET-hours) | 10.0 (12.3) | 9.9 (15.5) | 0.96 |
| Categorical Variables | VMS (Yes) | VMS (No) | p-value* |
| % (N) | % (N) | ||
| Agatston score > 0 | 54.9 (385) | 49.5 (103) | 0.21 |
| Race/ethnicity | 0.009 | ||
| - White | 73.8 (517) | 76.9 (160) | |
| - Black | 18.8 (132) | 10.6 (22 | |
| - Hispanic | 5.4 (38) | 9.6 (20) | |
| - American Indian | 0.9 (6) | 1.0 (2) | |
| - Asian/Pacific Islander | 0.3 (2) | 0.0 (0) | |
| - Unknown | 0.9 (6) | 1.9 (4) | |
| Baseline income (< $35,000) | 38.8 (262) | 39.5 (77) | 0.86 |
| Education | 0.59 | ||
| - High school/GED or less | 26.2 (182) | 24.2 (50) | |
| - School after high school | 43.5 (302) | 47.3 (98) | |
| - College degree or higher | 30.4 (211) | 28.5 (59) | |
| HRT arm (CEE group) | 50.2 (352) | 51.9 (108) | 0.67 |
| HRT use status | <0.01 | ||
| - Never used | 42.1 (295) | 60.6 (126) | |
| - Past user | 34.5 (242) | 21.6 (45) | |
| - Current user | 23.4 (164) | 17.8 (37) | |
| Bilateral oophorectomy | 38 (257) | 39.3 (75) | 0.79 |
| Alcohol consumption | 0.32 | ||
| - Non Drinker | 45.1 (315) | 51.0 (106) | |
| - <= 1 drink/day | 45.6 (318) | 40.4 (84) | |
| - > 1 drink/day | 9.3 (65) | 8.7 (18) | |
| Antihypertensive medication use at Baseline | 26.0 (182) | 20.7 (43) | 0.11 |
| Baseline hypertension | 0.4 | ||
| - Normotensive: < 120/80 and no meds | 28.7 (201) | 33.2 (69) | |
| - Prehypertensive: [120,140)/[80,90) and no meds | 33.4 (234) | 32.7 (68) | |
| - Hypertensive: >= 140/90 or on medication | 37.9 (266) | 34.1 (71) | |
| History high cholesterol or taking lipid-lowering med | 9.8 (69) | 11.1 (23) | 0.66 |
| Antihyperlipidemic use (including statins) | 4.9 (34) | 6.3 (13) | 0.47 |
| History treated diabetes or taking anti-diabetic med | 5.0 (35) | 4.3 (9) | 0.66 |
| Family History of MI | 47.2 (317) | 47.4 (93) | 0.98 |
*
Adjusted for age