Table 3.

Median raw SNR and normalized SNR (nSNR: cm⁻³ min^−1/2) values for all spectroscopic imaging techniques for NAA in 10 volunteers. Standard deviation between the 10 scans is shown (for nSNR only) as median ± SD. Median metabolite ratios are also shown for each technique (Cho:NAA and Cre:NAA). Voxels were considered to have aliased lipid if Lip SNR was greater than 25% of median NAA SNR in NAWM. Flyback data were not acquired on one volunteer and symmetric data were not acquired on another.

Encoding Technique	NAA raw SNR	NAA nSNR	Cho:NAA	Cre:NAA	% of voxels with aliased lipid
Traditional MRSI	46.28	10.10 ± 1.09 (22.28%)	0.48	0.39	0.0 ± 5
Ellipsoidal MRSI	68.75	9.22 ± 1.07 (23.48%)	0.49	0.40	0.0 ± 7
SENSE MRSI (Rx=2)	20.54	6.16 ± 1.14 (23.19%)	0.48	0.43	16.2 ± 27
SENSE w/REG	27.05	8.11 ± 1.74 (24.49%)	0.49	0.42	12.3 ± 20
Flyback EPSI	25.87	8.29 ± 0.83 (21.12%)	0.51	0.39	2.0 ± 4
Symmetric EPSI	24.73	8.05 ± 0.76 (26.18%)	0.51	0.37	0.0 ± 2
Symmetric w/ramps	21.89	8.45 ± 1.14 (24.46%)	0.50	0.37	2.2 ± 4