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. Author manuscript; available in PMC: 2011 Feb 10.
Published in final edited form as: Mol Genet Metab. 2008 Mar 17;94(2):240–247. doi: 10.1016/j.ymgme.2008.01.015

Fig 4.

Fig 4

Efflux of cholesterol from the basolateral surface of BeWo cells to different acceptors. The apical side of cells were labeled with [3H]cholesterol for 24 h. After labeling, cells were washed and incubated with SFM (none) or HDL (11.5 µg phospholipid/ml) from 3 adults, one SLOS fetus, and 5 control fetuses or plasma (10%) from one of each type of subject. An aliquot of the basolateral media was counted, and the data are presented as the amount of [3H]cholesterol effluxed as a percentage of cellular [3H]cholesterol at time 0. Using HDL as an acceptor, data are presented as means of different samples ± 1 SD for the different subjects. *Significant differences (P < 0.05) between acceptors and SFM (none) are shown. Using plasma as an acceptor, data are presented as means ± 1 SD for triplicate assays for one control fetus, one SLOS fetus, and one adult.