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Antibacterial activity and inhibition of bpmFabI-1 by triclosan and the diphenyl ethers
|
B. thailandensis |
||||||
|---|---|---|---|---|---|---|
| Inhibitor | K1 (nM) | K2 (nM) | B. pseudomallei MIC (mg/L) | E264 MIC (mg/L) | Bt38 MIC (mg/L) | |
| Triclosan |  |
1.57 ± 0.13 | 1096 ± 74 | 30 | 30 | 0.2–0.5 |
| PT01 |  |
0.51 ± 0.04 | 910 ± 101 | 70 | 70 | 0.2–0.5 |
| PT02 |  |
1.30 ± 0.10 | 361 ± 14 | >250 | >250 | 1.2 |
| PT03 |  |
1.80 ± 0.20 | 428 ± 20 | >250 | >250 | 33 |
