Table 3.
Categories of mice | Ultimate load at failure (N) | Linear stiffness (N/mm) | Maximal distension (mm) | Energy absorbed (N–mm) |
---|---|---|---|---|
WT (n=10) | 2.78±0.20 | 1.18±0.15 | 6.83±1.05 | 9.23±2.04 |
LOXL1−/− (n=5) | 1.91±0.50 | 1.20±0.17 | 7.18±2.68 | 7.71±4.19 |
WT without level I (n=4) | 2.37±0.28 | 1.17±0.10 | 6.56±1.24 | 8.32±1.59 |
WT without level II (n=4) | 2.82±0.61 | 1.17±0.20 | 6.95±0.42 | 9.52±1.49 |
WT without levels I and II (n=4) | 1.85±0.25 | 1.24±0.29 | 4.88±1.30 | 5.11±1.93 |
p values | ||||
WT vs. LOXL1−/− | 0.001 | >0.99 | 0.99 | 0.68 |
WT vs. WT without level I | 0.23 | >0.99 | >0.99 | 0.94 |
WT vs. WT without level II | >0.99 | >0.99 | >0.99 | >0.99 |
WT vs. WT without levels I and II | 0.001 | 0.97 | 0.13 | 0.04 |
LOXL1−/− vs. WT without level I | 0.32 | 0.99 | 0.92 | 0.98 |
LOXL1−/− vs. WT without level II | 0.02 | 0.99 | 0.99 | 0.65 |
LOXL1−/− vs. WT without levels I and I | >0.99 | 0.99 | 0.17 | 0.39 |
Data are presented as mean+standard deviation, p values are generated from post hoc pairwise comparisons between WT and all other groups were made using Dunnett's multiple comparisons procedure. Similar analysis performed excluding WT and comparing all groups to LOXL1−/−